The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Booking Overview

The Human Upgrade is a longevity and performance show where Dave Asprey digs into biohacking protocols and the underlying science with high-credibility experts. For PR professionals, it’s a strong platform for researchers and founders in neurotech, cellular longevity, functional medicine, and related health innovation—often paired with product validation and translational clinical claims.

Metrics

Episodes: 1528

Frequency: Multiple_weekly

Rating: 4.6/5.0

Estimated listeners: >100k

Gender skew: Male

Location: USA

YouTube: 265.0k subscribers

Instagram: 1.0M followers

30s Ad: 4800 - 5908, 60s Ad: 5723 - 6831

Contact Form

Contact form available - Official Form

Host

Dave Asprey - Founder of Bulletproof Coffee and a leading figure in the modern biohacking movement, known for translating longevity/performance research into practical protocols. Author (including multiple New Y...

Booking Intelligence

Booking Requirements

high
Typical Credentials:  
Deep technical credibility (MD/PhD or equivalent research credentials), track record in translational longevity/performance science or neurotechnology; frequently includes founders/executives who can speak both to mechanisms and real-world validation (published research, patents, clinical studies, or large-scale research/partnerships).
Required Achievements:  
Peer-reviewed publications in major journals, Founded or led a company with a longevity/performance product or platform, Patents related to longevity or biomedical mechanisms, Evidence-based study outcomes (clinical, observational, or controlled research), Notable education/teaching leadership in healthspan or performance medicine

Recent Guest Discussions

Dr. Patrick Porter - Brainwave Entrainment And Light/sound Neurotechnology (e.g., 40hz Gamma), Amyloid/dementia-related Mechanisms, Mitochondrial And Nitric Oxide Pathways, Circadian And Sleep Reset Claims, And Ai-personalized Training Protocols.

Chris Rinsch - Urolithin A, Mitophagy/mitochondrial Turnover, Gut Microbiome-derived Postbiotics, Clinical Improvements In Immune Markers And Inflammation, And Translational Longevity/healthspan Development.

Dr. Molly Maloof - Relationship And Social Biology Impacts On Longevity, Neurobiology Of Love/attachment, Cell Danger Response, Oxytocin/psychedelic/hormetic Frameworks, Regenerative Medicine And Peptide Approaches.

Recent Topics

Longevity, Biohacking, Neuroscience, Mitochondria, Functional Medicine, Neurotechnology, Cellular Health, Sleep, Fasting, Immunology

Episodes

Here's the recent few episodes on
The Human Upgrade: Biohacking for Longevity & Performance
:

The Doctor With Answers To Your Mystery Symptoms | Jessica Peatross : 1473

May 26, 2026

The Hidden Causes of Brain Fog, Anxiety, and Chronic Illness: Mold, Parasites, Histamine, and Low Cortisol  If you're exhausted, inflamed, and can't figure out why, the answer might be hiding in your histamine, your hormones, your home, or something living inside you that your doctor will never test for.  Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR  Host Dave Asprey sits down with Dr...

The EXACT Japanese Formula To Live Past 100+ (Simple Steps) : 1471

May 24, 2026

In this video, I break down the exact biological mechanisms keeping men in Okinawa, Japan, physically dominant and mentally sharp past 100. You don't need million-dollar lab work or intense weight training to reverse your biological age. Instead, these centenarians leverage five specific lifestyle protocols to naturally upgrade their biology. I explain the hard science behind how eating to 80% full shuts down the constant growth signaling that accelerates cellular aging. We'll also cover why ...

This Epic Device Gives You A SUPERBRAIN : 1472

May 22, 2026

Light Therapy, 40Hz Gamma & Brainwave Entrainment: How BrainTap Resets Sleep, Clears Brain Fog, and Boosts Productivity by 26% Your brain is being starved of the one nutrient it needs most, and it is not a supplement, not a nootropic, not a fasting protocol. It is light, and a 40 hertz flicker delivered at the right frequency can break up amyloid plaque, reset your nervous system, and get you 26 percent more productive in a single session.  -Watch this e...

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