Episodes: 311
Frequency: Weekly
Rating: 4.7/5.0
Estimated listeners: 1k-10k
Gender skew: Unknown
Location: USA
YouTube: 17.5k subscribers
Instagram: 1.3k followers
Publicly listed emails
trikomes@protonmail.com
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Nick Jikomes - Scientist and podcast host who curates and synthesizes research on how food, drugs, and ideas influence the mind and body, emphasizing primary evidence and independent analysis.
Nephi Stella - Endocannabinoid Biology, Cannabinoid Therapeutics, Adolescent THC, Cannabinoid Receptors, And Treatments For Metabolic And Neurological Conditions.
Pinchas Cohen - Mitochondrial Peptides, Genetic Variation, Longevity, Muscle Preservation, Metabolism, Neurodegeneration, And Emerging Peptide Therapies.
Isaac Chiu - Neuro-immune Interactions, Pain, Itch, Infection, Inflammation, Gut Barrier Protection, Allergy Priming, And Inflammatory Memory.
Changhan David Lee - Mitochondrial Peptides, Mots-c, Cellular Stress Signaling, Metabolism, Immune Modulation, And Aging-related Health.
Rahi Sarbaziha - Ghk-copper, Peptides, Skin Health, Tissue Repair, Hair Health, Administration Routes, Safety, And The Need For Additional Human Research.
Effects of Dietary Sugars on Human Health | Kimber Stanhope | Episode 307
September 15, 2026
Send us Fan MailControlled human feeding trials show added fructose raises liver fat, triglycerides, uric acid, and insulin resistance at real-world doses.TOPICS DISCUSSED:Glucose vs Fructose in the Liver: Glucose and fructose are handled by the liver in distinct ways.Natural Sugars vs Processed Sugars: Whole fruit is mostly water, fiber, and micronutrients at modest sugar density; cookies and sodas pack far more sugar per weight and are easier to overconsume.HFCS on Store Shelves: Industry c...
Human Brain Evolution & Development | Christopher Walsh | Episode 306
August 28, 2026
Send us Fan MailHow genomics is used to study what makes a human brain, and how genetically damaged neurons get removed.TOPICS DISCUSSED:Scale & Size: A human brain is about three times a chimpanzee brain by mass, but the larger change is extra association cortex and extra upper-layer circuits that talk mostly to other cortex.When Development Ends: Most cortical neurons are born before birth. Myelin and other glia keep forming into the twenties. Synapses keep changing after that.Broken Ge...
Endocannabinoid Biology in Health & Disease | Nephi Stella | Episode 305
August 20, 2026
Send us Fan MailThe biology of endogenous cannabinoids & history of cannabinoid-based therapeuticsTOPICS DISCUSSED:Anandamide vs 2-AG: The two major endocannabinoids with a shared arachidonic acid backbone but distinct head groups biological roles.On-demand production: Calcium-dependent enzymes release cannabinoids from membranes in response to neuronal activity patterns.Trafficking: Fatty acid binding proteins and extracellular microvesicles traffic endocannabinoids within and between ce...
Publicly listed emails
trikomes@protonmail.com
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