What Could Go Right?

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Why We Can't Picture a Good Future Anymore | With Ari Wallach

September 11, 2026

Are we trapped in a cultural doom loop that forces us to fear the future instead of dreaming of a better one? In this episode, futurist Ari Wallach joins host Zachary Karabell to examine why modern society defaults to short-termism and how we can fundamentally redesign our approach to tomorrow. They dive deep into Wallach's "Longpath" framework, exploring how Western death anxiety, a deficit of transgenerational empathy, and a cultural obsession with dystopian media hinder our ability to tack...

AI Designed a Cancer Therapy, Cyborg Bugs Are Saving Lives, and the Farmworkers Who Fought Back

September 07, 2026

What if you never have to wear a pink ribbon again? For years, experts called the medical dream of a personalized cancer vaccine impossible. Now, a new therapy written by an algorithm is making it happen. We're also talking about how Australian cyborg cockroaches could come to the rescue at natural disasters, and we get into the alliance that brought a California farming empire to its knees and created a historic labor movement. For transcripts, to join the newsletter, and for more informati...

Alien Civilizations, Mars Colonization & Humanity in the Age of AI | With Dr. Dakotah Tyler

September 02, 2026

Is interest in space dying, or are we on the brink of our greatest interstellar discoveries? In this episode of What Could Go Right, Zachary Karabell sits down with Dr. Dakotah Tyler, an astronomer and astrophysicist who pivoted from a promising college football career to unraveling the mysteries of the universe.They discuss the existential threats and promises of large language models, questioning whether tech leaders can manipulate human thought and if our innate drive to explore is being o...