Vital Signs with Jacob Effron and Nikhil Krishnan

Jacob Effron, Nikhil Krishnan

jeffron@redpoint.com

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Booking Overview

Vital Signs is a healthtech-focused show where the hosts dig into emerging trends and sub-sectors through conversations with policy leaders, startup founders, and industry executives shaping clinical and operational change. It’s especially strong for AI-in-health, health economics, and implementation questions like care delivery workflows and reimbursement.

Metrics

Episodes: 69

Frequency: Biweekly

Rating: 5.0/5.0

Estimated listeners: 1k-10k

Gender skew: Male

Location: USA

YouTube: 4.1k subscribers

Instagram: 75.0k followers

Contact Information

jeffron@redpoint.com

For verified host and producer emails, sign up to view.

Host

Jacob Effron - Co-host of Vital Signs, where he and Nikhil Krishnan explore cutting-edge trends in healthtech and the people shaping them, including policy leaders, startup founders, and industry executives.

Nikhil Krishnan - Co-host of Vital Signs, where he and Jacob Effron explore cutting-edge trends in healthtech and the people shaping them, including policy leaders, startup founders, and industry executives.

Booking Intelligence

Booking Requirements

medium
Typical Credentials:  
Policy leaders, startup founders/CEOs, and industry executives in healthtech (often in clinical AI, digital health, remote monitoring, reimbursement/payment models, and healthcare quality measurement).
Required Achievements:  
Lead roles at venture-backed or scaled healthtech companies, Published outcomes/cost studies or major evidence in peer-reviewed venues (in some cases), Fundraising and/or notable Series rounds (in some cases), Recognition via participation in major AI research/ecosystem events (in some cases)

Recent Guest Discussions

Chris Altchek - AI For Chronic Disease Management; Remote Patient Monitoring; Hospital-at-home Scaling; AI Voice Agents; CMS Payment Models Like Access; Digital Health Responsibility To Engage New Reimbursement Models

Nick Reber - Measuring Doctor Quality And Physician Quality Variation; Physician Scoring Methodologies; Value-based Care Incentives And Patient Behavior; AI Reshaping Healthcare Front Door; Durable AI Health Businesses Beyond 2030

Shiv Rao - Clinical AI Direction; Doctors Who Code; Prototype-to-production; Regulation And Partnerships; Customization Vs Reliability; Pre-visit Workflows And Triage

Recent Topics

Healthtech, Artificial Intelligence, Healthcare Policy, Digital Health, Reimbursement

Episodes

Here's the recent few episodes on
Vital Signs with Jacob Effron and Nikhil Krishnan
:

Ep 69: Cadence Founder Chris Altchek on the Future of Chronic Disease Care

June 24, 2026

Chris Altchek, founder and CEO of Cadence, joins Nikhil and Jacob to discuss how AI is changing the way chronic disease gets managed at scale. Cadence treats 100,000 patients a day across major health systems and has published some of the largest cost and outcomes studies in the space, including a nearly 17,000-patient analysis in Mayo Clinic Proceedings and a 24,000-patient study in the Journal of the American College of Cardiology. The conversation covers the three phases remote patient mon...

Ep 68: Garner Health Founder on Measuring Doctor Quality, The AI Landscape & What Improves Healthcare

May 29, 2026

Nick Reber, CEO and founder of Garner Health, joins Jacob and Nikhil to walk through what is arguably one of the most structurally underrated problems in American healthcare: that the single biggest driver of cost and quality variation isn't which hospital system you use or whether your plan is value-based — it's which individual doctor you see. Nick traces the intellectual journey from his time at Oscar Health, where he first encountered 4x variation in complication rates across physicians a...

Ep 67: Abridge Leaders on AI-Native Healthcare, Doctors Who Code, and the Future of Clinical AI

April 30, 2026

A couple weeks ago, Michał Nedoszytko placed third globally at Anthropic's hackathon out of 13,000 participants. He was the head of cardiology at a hospital in Brussels at the time. Now he is Clinical Scientist at Abridge. On this episode of Vital Signs, Nikhil and I sat down with Abridge's CEO Shiv Rao and Michal to chat about how the hire came together, what changed with Opus 4.6 that let a cardiologist ship a working MVP in 40 minutes, and where they both think clinical AI goes next.   (0:...

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