The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

Relational Foundation Models for Enterprise Data with Jure Leskovec - #768

May 21, 2026

In this episode, Jure Leskovec, co-founder and chief scientist at Kumo and professor of computer science at Stanford, joins us to explore two fronts of his work: AI for science and relational deep learning. We begin with AI Virtual Cell, a multiscale effort to learn data-driven representations from proteins to cells to patients using single-cell RNA-seq data, protein language models like ESM, and structure models like AlphaFold—without hand-encoding biology. Jure then dives into relational de...

How to Find the Agent Failures Your Evals Miss with Scott Clark - #767

May 07, 2026

In this episode, Scott Clark, co-founder and CEO of Distributional, joins us to explore how teams can reliably operate and improve complex LLM systems and agents in production. Scott introduces a Maslow’s hierarchy of observability: telemetry for logging, monitoring for known signals, and post-production or online analytics to surface unknown unknowns. We dig into examples of real-world failures Scott’s team has seen in production systems, such as “lazy” tool-use hallucinations that standard ...

How to Engineer AI Inference Systems with Philip Kiely - #766

April 30, 2026

In this episode, Philip Kiely, head of AI education at Baseten, joins us to unpack the fast-evolving discipline of inference engineering. We explore why inference has become the stickiest and most critical workload in AI, how it blends GPU programming, applied research, and large-scale distributed systems, and where the line sits between inference and model serving. Philip shares how research-to-production can move in hours, not months, and why understanding “the knobs” of inference—batching,...