On with Kara Swisher

Pretty Tough with Maria Sharapova: Chelsea Handler

May 25, 2026

Happy Memorial Day from all of us at On with Kara Swisher! Today, we’re bringing you a special episode of "⁠Pretty Tough⁠," a new podcast from the Vox Media Podcast Network hosted by tennis star and entrepreneur Maria Sharapova. Each week, Maria sits down with high-achieving women across industries for candid, wide-ranging conversations about their pursuit of excellence without apology. In this episode, Maria speaks with comedian and best-selling author Chelsea Handler, who's built a caree...

Is It Possible to Hack Your Body for a Longer Life?

May 23, 2026

From GLP-1’s to peptides to hyperbaric chambers, we’re awash in medical information and wellness trends. But what do we really know about improving longevity and increasing your healthspan?  This is the first episode of the Hacking Longevity series. Kara breaks down the best advice for actually living longer (spoiler alert: it’s boring, and you probably already know it), and hears from some members of her own medical team about how to make the best health decisions.  First is Dr. David ...

Why FCC Chair Brendan Carr Is a Dangerous Moron

May 21, 2026

Kara is joined by FCC Commissioner Anna Gomez, Knight First Amendment Institute executive director Jameel Jaffer, and The Verge editor-in-chief Nilay Patel to discuss FCC Chairman Brendan Carr’s escalating campaign against media companies, broadcasters and speech President Trump dislikes.  They discuss Carr’s threats against ABC/Disney, his attempts to revive old rules around “equal time” and “news distortion,” and the Trump administration's broader push to control federal agencies. They a...