Booking Overview
Metrics
Episodes: 596
Frequency: Weekly
Rating: 4.7/5.0
Estimated listeners: 10k-100k
Gender skew: Male
Location: USA
YouTube: 82.9k subscribers
Contact Information
Publicly listed emails
dom@colossus.com
help@colossus.com
dom@joincolossus.com
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Host
Patrick O'Shaughnessy - Investor, entrepreneur, and founder and CEO of Positive Sum, an investment firm and venture studio.
Booking Intelligence
Booking Requirements
Recent Guest Discussions
Neil Movva - AI Inference Economics, Long-running AI Agents, Gpus, Computing Infrastructure, Energy, And The Competitive Outlook For AI Companies.
Ben Thompson - Big Tech, China, AI Economics, Capital Requirements, Cloud Computing, Platform Strategy, And Technology Markets.
Eric Vishria - Software And Cloud Investing, AI Adoption, Enterprise Technology, Infrastructure, Robotics, And Lessons For Founders And Investors.
Gavin Baker - Public Technology Markets, AI Infrastructure, Gpus, Memory Supply, Credit, Open-source AI, And Investment Risk.
Sam Altman - AI Development, Computing Infrastructure, Data Centers, Chips, Open Source, Robotics, Employment, And The Future Impact Of Abundant Intelligence.
Recent Topics
Episodes
Walter Russell Mead - How America Keeps Winning - [Invest Like the Best, EP.490]
September 08, 2026
My guest today is Walter Russell Mead. Walter is a columnist at the Wall Street Journal and the author of Special Providence and God and Gold, two of the best books written on American power. He has spent decades studying how the United States came to dominate the world, and our conversation is about whether it can keep doing so. Walter lays out the five step playbook that carried the Dutch, then the British, then America to global leadership, and why the same pattern keeps beat...
Sarah Guo - Funding the Frontier - [Invest Like the Best, EP.489]
September 01, 2026
My guest today is Sarah Guo, founder and managing partner of Conviction, the venture firm she built to back AI-native companies from their earliest days. Sarah has become one of the most sought-after early-stage investors in AI, often the first check into the companies defining the frontier. In this conversation, we go inside that frontier: what the small group of people actually building AI believe right now, why some of the field's best researchers are wrestling with their own...
Neil Movva - Making AI 10x Cheaper - [Invest Like the Best, EP.488]
August 25, 2026
My guest today is Neil Movva, founder of Sail. Sail is building what Neil calls a token factory, an inference company designed for a specific kind of future, one where AI agents run in the background for hours or days at a time rather than answering a human in real time. In that world, latency matters less and cost matters more, and Neil has built the whole company around driving the cost of a token as low as it can possibly go. What makes this conversation special is that it is one o...
Publicly listed emails
dom@colossus.com
help@colossus.com
dom@joincolossus.com
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