We're not getting any younger... yet.

Hanadie Yousef: Cracking the Secretome Code

April 01, 2026

In this episode, Buck scientist Brianna Stubbs joins Hanadie Yousef, Co-Founder of Juvena Therapeutics, to discuss the cutting-edge of longevity science. Dr. Yousef shares how Juvena is leveraging AI and the secretome—the proteins secreted by stem cells—to develop therapies that target muscle wasting and promote tissue regeneration. From the potential and risks of GLP-1 drugs to the role of AKT signaling in muscle health, this conversation explores how we can move beyond "snake oil"...

Cynthia Kenyon: Switching on Resilience

March 18, 2026

Eric Verdin sits down with Dr. Cynthia Kenyon, a true pioneer in the field of geroscience and the Vice President of Aging Research at Calico. Dr. Kenyon recounts the revolutionary discovery that aging is not merely a process of "wearing out," but is a genetically regulated biological program. In 1993, Cynthia’s pioneering discovery that a single-gene mutation could double the lifespan of C. elegans roundworms while preserving function sparked an intensive study of the molecular biol...

Ana Maria Cuervo: Cellular Recycling

March 04, 2026

What if the secret to a longer, healthier life isn’t found in a new supplement or a complex medical procedure, but in your cells' own innate ability to "take out the trash"? In this episode, host Eric Verdin is joined by Dr. Ana Maria Cuervo, a pioneer in the biology of aging and professor at the Albert Einstein College of Medicine. The conversation explores the critical roles of proteostasis—the cell's protein quality control factory—and autophagy, the body's natural...