The Optispan Podcast with Matt Kaeberlein

Matt Kaeberlein, Dr. Nicki Byrne

Booking Overview

The Optispan Podcast with Matt Kaeberlein focuses on evidence-based longevity and healthspan science, with an emphasis on what actually improves outcomes rather than hype. It’s a strong fit for PR outreach to researchers, clinicians, and translational science leaders who can discuss neurodegeneration, metabolic health, and actionable prevention.

Metrics

Episodes: 168

Frequency: Irregular

Rating: 4.6/5.0

Estimated listeners: 1k-10k

Gender skew: Male

Location: USA

YouTube: 18.0k subscribers

30s Ad: 26 - 32, 60s Ad: 31 - 37

Contact Information

optispanpodcast@gmail.com

Contact Form

Contact form available - Official Form

Host

Matt Kaeberlein - Matt Kaeberlein is a longevity-focused researcher and clinician/science communicator associated with evidence-based approaches to improving healthspan. On this show, he frames modern medicine as di...

Dr. Nicki Byrne - Nicki Byrne is a Clinical Director featured as a co-host/AMA participant (not a recurring named interviewer role in the provided data). Her contributions center on supplement science and translatin...

Booking Intelligence

Booking Requirements

medium

Typical Credentials:

PhD/MD-level researchers or clinician-scientists with strong publication records in neuroscience, geriatrics/neurodegeneration, cardiometabolic health, and/or translational biomarker-driven prevention; often with credibility in study design, trials, and evidence appraisal; sometimes domain expertise in performance or applied physiology.

Required Achievements:

Academic leadership (associate professor/professor-level) or department/team science leadership, Published research in peer-reviewed journals relevant to healthspan or neurodegeneration, Authored/edited books or major reports translating research into actionable frameworks, Involvement with clinical trials or translational studies

Recent Guest Discussions

Dr. Tommy Wood - Brain Longevity; Neuroplasticity; Dementia Prevention Drivers; Evidence On Diet (including Keto), Biomarkers, Supplementation, Sleep/performance Metrics; Translational Research And Mechanistic Frameworks

Recent Topics

Longevity, Healthspan, Neuroscience, Dementia, Metabolism, Cardiovascular, Biomarkers, Prevention, Nutrition, Supplements

Episodes

Here's the recent few episodes on

The Optispan Podcast with Matt Kaeberlein

Neuroscientist Reveals What's Actually Working for Brain Longevity (with Dr. Tommy Wood)

April 06, 2026

What if you had more control over your brain's future than you think? Dr. Tommy Wood, neuroscientist, Associate Professor of Pediatrics at the University of Washington, and head of science for motorsport at Hintsa Performance, joins Dr. Matt Kaeberlein to discuss his new book, The Stimulated Mind. From the science of neuroplasticity to the real drivers of dementia prevention, this episode is packed with evidence-based, actionable insight.Timestamps:0:00 — Introduction: Brain fog, burnout ...

Longevity Doctors Rank the Most Hyped Supplements (AMA with Dr. Kaeberlein and Dr. Byrne)

April 03, 2026

Dr. Matt Kaeberlein and Clinical Director Dr. Nicki Byrne tackle your most pressing supplement questions in this AMA episode, cutting through the hype to give you science-backed answers you can actually use. From CoQ10 and statins to sulforaphane influencer hype, creatine and kidney disease, and why a popular longevity doctor may be losing Matt's trust, this episode covers a lot of ground. If you've ever wondered which supplements are worth your money and which ones belong in the tras...

New Discovery: This Test Finds Cancer Before It Even Exists (Reaction to Galleri Trial)

March 27, 2026

The Galleri multi-cancer detection test made headlines when its landmark NHS trial failed to meet its primary endpoint, sending Grail's stock down nearly 50%. But does that mean Galleri is useless? Not exactly. In this episode, Dr. Matt Kaeberlein breaks down what the NHS Galleri trial actually measured, why missing a primary endpoint doesn't tell the whole story, and what the results mean for three distinct groups: the general population, high-risk individuals, and people considering the tes...

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